Annoying Questions I'd Like Answered...

Shiritai · Post by **Shiritai** » Tue Mar 03, 2015 6:11 pm

tussock wrote:I don't think you understood your link, Shiritai, which is an add for a pill.

I don't think I understood your reply. I only took issue with your statement that "The process of balancing blood calcium is not adding or removing structural elements from bone", while your post was... a lecture on stuff I already knew.

And an ad for a pill? Really? Why don't you tell me what you think my link said; at least that might be entertaining.

tussock · Post by **tussock** » Wed Mar 04, 2015 4:50 am

Right. That'd be typical for me then. I don't see how it can. Everything that is removed leaves a rough surface, just right to cause regrowth in proportion to local stresses. Over the time spans required to significantly weaken a bone, you've got to have reduced stress on the bone (or an inability to fix bone at all) to really weaken it.

So what you're "losing" is necessarily useless weight. The structural bits that you use cannot be lost by balancing blood calcium, but the bits you are not using will be, and those will be lost regardless of your blood calcium levels.

Logic. The balancing of blood calcium is not changing the strength of your bones, even though the process which constantly updates the strength of your bones is also tweaked at times to help balance blood calcium. I guess I used the wrong terminology for that up front, and here I am trying to figure out why you're disagreeing.

link wrote:A new drug has been developed for the treatment of osteoporosis that targets the interaction between RANK and RANKL. Denosumab is monoclonal antibody that binds to RANKL; thus it mimics the effect of osteoprotegerin. Denosumab (marketed as Prolia®) was approved for the treatment of osteoporosis in June 2010.

That's what I thought your link said. Information on how bones work, bought to you by the company with a registered trademark and patent on the drug which changes that. Now sponsoring your education.

Maj · Post by **Maj** » Wed Mar 04, 2015 6:18 am

icyshadowlord wrote:Why is a PM I have tried to send last week just sitting in my Outbox, instead of going to the Sentbox?

I think that means it's still unread.

Username17 · Post by **Username17** » Wed Mar 04, 2015 7:21 am

Tussock, you're a damn idiot, you know that? Every person's bones achieve a maximum density sometime in their twenties and gradually demineralize as they get older. Sooner or later, everyone gets osteoporosis, and that's bad. It happens to people who have less calcium in their bones at age 22 faster than it happens to people who have more.

Vitamin D is more important than dietary calcium, but dietary calcium still has an effect. It's an equilibrium process, so obviously changing any of the terms changes the rate of change.

-Username17

Count Arioch the 28th · Wed Mar 04, 2015 10:05 am

I've made bone broth before and leached out the calcium from the bones. So, if I add vinegar directly to my bloodstream at a concentration of about 2 tablespoons per gallon, could I de-calcify my bones?

Username17 · Post by **Username17** » Wed Mar 04, 2015 11:27 am

Count Arioch the 28th wrote:I've made bone broth before and leached out the calcium from the bones. So, if I add vinegar directly to my bloodstream at a concentration of about 2 tablespoons per gallon, could I de-calcify my bones?

Yes.

You might also die.

-Username17

Stahlseele · Post by **Stahlseele** » Wed Mar 04, 2015 2:25 pm

Why do Smart TV's not react to stuff that comes from their own speakers?
So for example, if the Smart-TV has the voice activation command "shut down" for switchting it off and you watch a movie or TV series where somebody says "shut down", why does the TV not get switched off? @.@

Or a clapper device to applause on the TV?

TiaC · Post by **TiaC** » Wed Mar 04, 2015 5:56 pm

FrankTrollman wrote:
Count Arioch the 28th wrote:I've made bone broth before and leached out the calcium from the bones. So, if I add vinegar directly to my bloodstream at a concentration of about 2 tablespoons per gallon, could I de-calcify my bones?
Yes.

You might also die.

-Username17

Isn't your blood too well buffered for that to work though?

name_here · Post by **name_here** » Wed Mar 04, 2015 6:20 pm

Not if you jab an injection needle directly into your arm.

TiaC · Post by **TiaC** » Wed Mar 04, 2015 6:32 pm

name_here wrote:Not if you jab an injection needle directly into your arm.

No, I mean pH buffered. The pH of your blood shouldn't change much even if you put quite a bit of acid in it.

LeadPal · Post by **LeadPal** » Wed Mar 04, 2015 9:43 pm

Blood pH doesn't change easily, but when it changes at all the results are not good. Shooting up diluted vinegar would probably either do nothing or put you in a coma, with not much in-between.

name_here · Post by **name_here** » Wed Mar 04, 2015 10:56 pm

Adding acid to the blood would make the pH fall and then various processes would make it rise. I have no idea how quickly that would happen. Given that people have a lot of blood, it would probably take a considerable amount of acid to change pH enough for long enough to be dangerous, but I would not advise testing.

tussock · Post by **tussock** » Thu Mar 05, 2015 4:08 am

FrankTrollman wrote:Tussock, you're a damn idiot, you know that? Every person's bones achieve a maximum density sometime in their twenties and gradually demineralize as they get older. Sooner or later, everyone gets osteoporosis, and that's bad. It happens to people who have less calcium in their bones at age 22 faster than it happens to people who have more.

Vitamin D is more important than dietary calcium, but dietary calcium still has an effect. It's an equilibrium process, so obviously changing any of the terms changes the rate of change.

Yes, I know I'm an idiot, but I'm a curious one. Did your study of bone density occur, per chance, in a country where almost all people accumulate cars, office jobs, and a TV sometime in their early 20's? Which is to say, they live sitting their ass after an extended childhood?

Like, astronauts in orbit seriously lose bone mineral, very rapidly without heavy exercise routines (and still slowly with them). But then they get it back to normal over a few months back on earth. People who start lifting weights at retirement will be stronger at 75 than they ever have been in their lives, and will thus have stronger bones with greater mineralisation. The internet says people who start lifting after 40 never peak, they just get stronger until they give up or die.

They're not as strong as they would have been in their late 20's if they'd lifted since 18, because your peak power production seems to happen 25-30, for sprinters, Olympic lifters, and such, and that limits stress on the bones, and thus limits bone mineralisation.

But again, wikipedia (and the stuff it links) is pretty clear that people get osteoporosis because they get feeble, for various reasons (typically a lack of activity associated with immune response, pain, or failing energy production).

The basic cure for osteoporosis is making old people (and whoever else) lift weights. It just goes away. Old people can also be fit and have less coronaries and strokes.

So if you're getting weak, fucking do something about getting stronger. If you were already weak in your 20's, fucking fix that shit at some point. Also do not inject acid into your blood, that's crazy.

Blade · Post by **Blade** » Thu Mar 05, 2015 10:34 am

Stahlseele wrote:Why do Smart TV's not react to stuff that comes from their own speakers?
So for example, if the Smart-TV has the voice activation command "shut down" for switchting it off and you watch a movie or TV series where somebody says "shut down", why does the TV not get switched off? @.@

Or a clapper device to applause on the TV?

When you know what noise you create, it's easy to cancel it.
Basically you just listen to "the current sound - the sound I've created" (of course it's mathematically a bit more complex than that, but we've got good enough signal processing algorithms to do it).

Username17 · Post by **Username17** » Thu Mar 05, 2015 11:06 am

God dammit Tussock, your gross ignorance on this subject is extremely grating. Calcium deficiency is in fact extremely common and has real consequences. Most of it is secondary to vitamin D deficiency, but not all of it is. Telling people "lol, exercise more" is not helpful. It's not "the cure", it's a thing that helps in some cases. But if you have a primary or secondary calcium deficiency, all exercise is going to do is break the bones you have. Fuck.

hyzmarca · Post by **hyzmarca** » Thu Mar 05, 2015 8:22 pm

Greek debt crisis hypothetical:

What would happen if Greece hasically sold itself to some other country, such as Russia or China?

Say Russia agrees to pay Greece's debt, and in turn Greece is now a member state of the Russian Federation, with all that entails, rather than a sovereign state. But at the same time it refuses to pull out of the EU and the Eurozone.

angelfromanotherpin · Post by **angelfromanotherpin** » Fri Mar 06, 2015 2:17 am

I think the first thing that would happen would be a popular revolutionary uprising to put the heads of whoever made that deal on spikes, followed by a new government based chiefly on not honoring that deal. It is hard to overstate how much the Greeks fetishize their sovereignty, and how much their ethnic pride would be offended by becoming the subjects of a slavic nation.

Prak · Post by **Prak** » Mon Mar 09, 2015 4:18 am

Not so much an annoying question as a stupid one-

I asked a friend of mine if she'd like to accompany me to a local Irish pub on St. Patrick's Day. Because that's the closest I can come to actually asking someone out. She has yet to respond, but she is interested in trying an Irish Car Bomb.

Assuming she accepts my asking her out, I'd like her to be able to try one, and I'd like to avoid pissing off the potentially Irish national bartender. Is there a polite name to use when ordering an Jameson/Guinness boilermaker? Should we just order "a boilermaker with Guinness and Jameson?" If we just order a boilermaker, will an Irish pub likely use Guinness and Jameson/other Irish whiskey without us specifying?

erik · Post by **erik** » Mon Mar 09, 2015 5:49 am

Not knowing the bar in question, I'd suggest just describing the drink.

Schleiermacher · Post by **Schleiermacher** » Mon Mar 09, 2015 11:30 am

There's no politically correct name for an Irish Car Bomb, at least none that I'd expect people, even bartenders at Irish pubs in the US, to recognize.

In fact, quite apart from the name an Irish bartender might easily refuse to serve that drink at all, on general principles. Of course that's not a given, but I probably wouldn't risk it with a bartender I didn't know.

Trying to tiptoe around the issue by ordering "a Jameson/Guinness boilermaker" has its own issues - for one thing, a "proper" Irish Car Bomb also includes Irish Cream (which sounds revolting to me, but whatever) and for another, that's not a concoction that many people would randomly come up with. The bartender will most likely know what you're ordering and may or may not refuse to serve it, per above.

One might say that I'm being a bit overcautious, since it's just a drink in the end, but many people consider the whole idea of the ICB to be in very poor taste, and I don't really blame them.

Tl; dr: the bartender might not care, or might not make an issue of it even if he does, but personally I would not order an ICB, by name or description, from any Irish bartender I did not personally know.

It's a pretty straightforward drink to make though, and the ingredients are useful for a wide variety of things, so if you just want your friend to be able to try it, you could make it yourselves, at your place or hers.

Count Arioch the 28th · Mon Mar 09, 2015 12:10 pm

Schleiermacher wrote: Trying to tiptoe around the issue by ordering "a Jameson/Guinness boilermaker" has its own issues - for one thing, a "proper" Irish Car Bomb also includes Irish Cream (which sounds revolting to me, but whatever) and for another, that's not a concoction that many people would randomly come up with.

It tastes kind of like a milkshake, I shit you not. Irish car bombs are that dangerous kind of booze that tastes so good that you forget it can and will fuck you up very quickly.

My opinion is "fuck political correctness" in this case and just call it an Irish Car Bomb. YMMV, but judging by some of the crazy shit I've said to bartenders in my alcoholic days you're not very likely to offend a bartender, Irish national or no...

Post by **fbmf** » Mon Mar 09, 2015 2:06 pm

I am not Irish, but I have a decade of experience bar tending. In my tenure, I made a lot of ICB, especially on SPD. It is no more offensive than ordering a Royal Fuck, a Panty Dropper, or Alaskan Whore's Blood. It's just the name of a drink. When someone says it, I think of ingredients and glassware availability, not prima nocte, date rape, or frigid working girls.

The dozens of bartenders I know from all different walks of life operate the same way.

Game On,
fbmf

Count Arioch the 28th · Mon Mar 09, 2015 3:28 pm

I have to ask, what is Alaskan Whore's Blood? That's the only one I have never heard of.

Post by **fbmf** » Mon Mar 09, 2015 5:55 pm

Jagermeister and Rumple. Also called an oil spill.

Prak · Post by **Prak** » Mon Mar 09, 2015 6:01 pm

Thanks for the advice guys. If we go, I'll feel out the place, maybe see if anyone else orders one.

Looking the question up, some people joking respond with "a 9/11."

Which clearly should be Jack in budweiser or something of the sort.